Engineering nanoscopic hydrogels via photo-crosslinking salt-induced polymer assembly for targeted drug delivery.
نویسندگان
چکیده
We report the preparation of biodegradable nanoscopic hydrogels and their application for targeted drug delivery. The nanogel is synthesized in a template-free method by photo-crosslinking salt-induced polymer assemblies. With convenient incorporation of targeted lactosyl moieties, the nanogels efficiently deliver doxorubicin to HepG2 cells through receptor-mediated internalization.
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عنوان ژورنال:
- Chemical communications
دوره 46 20 شماره
صفحات -
تاریخ انتشار 2010